ZOCOR® has been available in the United States since 1992, and ZOCOR® has been prescribed for more than 6 million patients worldwide. Background A team of doctors and scientists designed a large-scale, long-term study to determine whether ZOCOR® (simvastatin), a cholesterol-lowering medicine, as an addition to diet, could help heart disease patients with high cholesterol live longer and avoid heart attacks. The study took about 6 years and involved 4,444 patients with coronary heart disease and high cholesterol. Clinical …showed first 75 words of 962 total…

…showed last 75 words of 962 total…particularly during the initial months of therapy and if the dose of either drug is increased. Your doctor may also monitor the level of certain muscle enzymes in your body, but there is no assurance that such monitoring will prevent the occurrence of severe muscle disease. ZOCOR is less effective in patients with the rare disorder known as homozygous familial hypercholesterolemia. Pediatric Use: ZOCOR is not recommended for children or patients under 20 years of age.